Difference Between Duodenal Ulcer and Gastric Ulcer

Edited by Diffzy | Updated on: August 14, 2022


Difference Between Duodenal Ulcer and Gastric Ulcer Difference Between Duodenal Ulcer and Gastric Ulcer

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A sore or unpleasant wound is all that is necessary to define an ulcer. There are various forms of ulcers, and each type's specific cause varies. The biggest contributing reasons to its causes, according to the study, include stress, eating more hot meals, contracting viral infections, and drinking alcohol. Anywhere in or on our bodies, ulcers can develop. While some of them rarely go away on their own, others need to be treated to avoid catastrophic problems. Typically, there are a variety of causes, symptoms, and treatments. Anywhere in or on our bodies, ulcers can develop. While some of them rarely go away on their own, others need to be treated to avoid catastrophic problems. Typically, there are a variety of causes, symptoms, and treatments.

Ulcer’s rip or tear the stomach's or the duodenum's protective lining. Duodenal ulcers are more common than stomach ulcers. Oesophageal ulcers are uncommon in general, but they often result from drinking alcohol or using specific medications, like antibiotics and anti-inflammatory treatments. Even though increased stomach acid production is one of the key causes, a recent study found that bacterial infection also plays a significant role in the development of ulcers. The bacteria Helicobacter pylori (H. pylori) are thought to be the root cause of over 80% of stomach ulcers and 90% of duodenal ulcers.

The Methods Listed Below Can Be Used To Spot Ulcers

Barium Swallow

This treatment involves having the patient ingest a thick, white barium liquid that covers the upper gastrointestinal system, allowing the doctor to view the stomach and small intestine on X-rays.


This procedure entails passing a little, lighted tube through the beginning of the small intestine and the stomach. The doctors may therefore discover any bleeding, ulcers, or abnormal tissues in the body.


A little bit of tissue is removed during a biopsy and evaluated in a lab.

Types of Ulcers

Peptic Ulcers

These can appear on the top part of the small intestine, the oesophagus, or the inner lining of the stomach. They develop when the stomach or intestine's lining is harmed by digestive juices. These are most frequently brought on by inflammation following an H. pylori infection and chronic pain medication use. Peptic ulcers come in three different varieties:

  • Stomach ulcers
  • Ulceration in the throat
  • Duodenal sores

Arterial Ulcers

The outside edge of the ankle, foot, toes, and heels might develop open sores called arterial ulcers. They arise from blood vessel injury brought on by inadequate blood supply to the tissue. Arterial ulcers have hairless skin, are red, yellow, or black, and cause leg pain.

Vein Ulcers

The most typical kind of leg ulcers, frequently develop on the leg, below the knee, and on the inside of the ankle. They develop as a result of vein injury brought on by insufficient blood flow back to the heart. Inflammation, swelling, itching skin, scabbing, and discharge are further possible symptoms.

Voice Ulcers

Small lesions or sores like these can develop in the mouth or around the gum line. They are also known as canker sores. Mouth ulcers can be brought on by aggressive teeth brushing, food allergies, hormonal changes, vitamin deficiency, bacterial infections, and other serious illnesses.

Generic Ulcers

These develop on the vagina, penis, anus, or surrounding areas of the genital organs. Genital ulcers are most frequently brought on by trauma, inflammatory diseases, STIs, and allergic reactions to cosmetics. They accompany a fever, rash, pain, itching, and swollen groin glands.

What Are An Ulcer's Initial Signs And Symptoms?

The early signs of ulcers can differ from person to person. The following are the significant symptoms in general:

Having abdominal ache and a burning sensation. The situation in the stomach gets worse mostly as a result of stomach acid. By consuming specific meals and taking medications that lower acid, the pain can be lessened.

  • A dislike fatty meal
  • Experiencing heartburn
  • The sensation of heaviness or swelling
  • Vomiting or nausea occasionally seems to be crimson or black in hue.
  • Bloody, dark stools
  • Observing alterations in appetite
  • Having an unforeseen loss of weight

Below Are Several Ulcer-Causing Factors

  • People with sedentary lifestyles or bad eating habits are more likely to develop stomach ulcers.
  • Alcohol misuse and pharmaceutical exposure, such as using certain antibiotics or anti-inflammatories, are common causes of oesophageal ulcers.
  • Additionally, eating fatty and oily foods, drinking alcohol, using smoke, and taking large amounts of caffeine can all cause ulcers. Each of these causes contributes to the build-up of stomach acids, which erode the duodenal, oesophageal, and stomach's protective lining.
  • Recent research suggests that one of the causes of peptic ulcers is a bacterial infection. For instance, H. pylori are found in 90% of duodenal ulcers and 80% of stomach ulcers.
  • Alcohol use, mental stress, smoking, and excessive use of over-the-counter medicines like ibuprofen, aspirin, or naproxen all contribute to the development of ulcers, especially in people who have H. pylori.
  • Older persons are more likely to get stomach ulcers. Growing older causes the pylorus to relax, allowing extra bile to leak into the stomach and eroding the stomach lining.
  • Cancerous stomach ulcers are more common in those with type A blood.
  • Those with blood group O develop duodenal ulcers. This is because persons with this blood group are unable to manufacture specific chemicals that are found on the blood cell surfaces that protect the duodenum's lining.

Duodenal Ulcer vs. Gastric Ulcer

The location of the ulcers in the digestive tract is the primary distinction between duodenal and gastric ulcers. A duodenal ulcer affects the first portion of the small intestine or duodenum, whereas a gastric ulcer affects the lining of the stomach.

Difference Between Duodenal Ulcer and Gastric Ulcer in Tabular Form

Table: Duodenal Ulcer vs. Gastric Ulcer
Parameters of Comparison
  Duodenal Ulcer
   Gastric Ulcer
On the other hand, duodenal ulcers develop in the duodenum, the small intestine's first section. Duodenal ulcers or duodenal ulcerations are other names for them.
Stomach ulcers are the most common type of ulcer. They typically develop on the inside lining of the stomach. Gastric ulcers are also known as stomach ulcers and peptic ulcers.
The first part of the small intestine is called the duodenum.
Occurs in the lining of the stomach.
Food or a cool drink can frequently reduce the burning caused by duodenal ulcers. They might also cause nausea, vomiting, upper abdominal pain, and loss of appetite.
Heartburn, motion sickness, appetite loss, and weight loss are just a few of the signs and symptoms of stomach ulcers.
Medication to reduce acid production, encourage healing, and reduce stomach acid are all part of the treatment for duodenal ulcers.
Treated by over-the-counter medicines such as proton pump inhibitors, H2 blockers, or antacids. Proton pump inhibitors and stomach acid reducers are more serious drugs that can be used to treat them if these don't work.
Most Impacts
More frequent in older people and usually takes time to develop.
Prevalent in young and middle-aged people.

What is Duodenal Ulcer?

Pancreatic ulcers are another name for duodenal ulcers. The duodenum or the initial portion of the small intestine is where this sort of ulcer typically develops. Low stomach acid levels, which may result from using an acid-blocking medication, are a common cause of duodenal ulcers. Additionally, they may be brought on by long-term conditions like diabetes and Crohn's disease. Small holes or erosions known as duodenal ulcers develop in the lining of the duodenum, the first segment of the small intestine that lies immediately after the stomach. Peptic ulcers include duodenal ulcers. A stomach (gastric) ulcer is another variety of peptic ulcers that develops in the stomach.

Proton pump inhibitors (PPIs) and H2 receptor blockers are two examples of medications used to treat duodenal ulcers. Other drugs, such as antibiotics, may also be used to treat them if the ulcer is brought on by an infection with Helicobacter pylori. Elderly people are more likely to develop duodenal ulcers, which normally progress slowly. While they occasionally result in significant pain or bleeding, they can nonetheless be uncomfortable.

Your medical history for peptic ulcers and any associated disorders will be discussed with your doctor, along with any medications you are now taking or have just started taking. Mention any NSAIDs that you are taking right now, notably aspirin, ibuprofen, diclofenac, or ketorolac. Your doctor will also listen to your bowel movements, feel for lumps, and check for bloating or swelling in your abdomen. It's crucial to call attention to any unpleasant or uncomfortable areas. Blood tests can be used to detect anaemia, Helicobacter pylori, a bacterium commonly associated with peptic ulcers, and infections. Stool samples, breath tests, or biopsies are frequently required for testing.

What is Gastric Ulcer?

An ulcer that is brought on by stomach acid is a gastric ulcer. Although they can develop anywhere in the stomach, gastric ulcers typically develop in the lower portion of the stomach. A chronic Helicobacter pylori infection, an overactive parietal cell, or a non-steroidal anti-inflammatory drug are the most common causes of stomach ulcers. Some people are more prone to developing stomach ulcers because they produce too much gastric acid. In other words, they happen when the duodenal or stomach lining is harmed. Consequently, a gastric ulcer is a tear or sore in the stomach or duodenum's lining. But it might also show up in the oesophagus or even later parts of the small intestine. Although they may occur anywhere along the stomach lining that is exposed to gastric juices, gastric ulcers typically occur in the stomach. Chronic Helicobacter pylori infection, an overactive parietal cell, or the use of non-steroidal anti-inflammatory drugs are the three main causes of gastric ulcers.

Different causes are responsible for these two factors. Helicobacter pylori are the most frequent cause of stomach ulcers. The digestive systems of two-thirds of the world's population have this bacterium. Its mode of transmission is unknown. However, some signs suggest that tainted food and water may be a cause of infection. Abuse of anti-inflammatories, which is continued, is another factor in stomach ulcer development. One of the medicines is ibuprofen. On the other hand, excessive alcohol and tobacco use unquestionably raises the risk of contracting this illness.

The doctor typically probes the patient about their suffering to diagnose this kind of pathology. The epigastric region is palpated because this is where this sort of ulcer produces the most intense discomfort. Blood samples are tested and ultrasound scans are done to confirm the diagnosis when further investigation is required. The best way to identify the kind and severity of a stomach ulcer is through gastroscopy. With this test, little samples of the injured tissue are typically removed and examined in a lab to identify the possible pathogen responsible.

Difference Between Duodenal Ulcer and Gastric Ulcer In Points

  • Duodenal ulcer may result from low stomach acid levels, which can be brought on by using acid-blocking medication or by long-term diseases like diabetes and Crohn's disease.
  • There are numerous causes of stomach and duodenal ulcers. Regular consumption of over-the-counter NSAIDs like aspirin or ibuprofen typically leads to stomach ulcers.
  • It's crucial to differentiate between the two types of ulcers. They typically ask for a variety of treatments. For instance, duodenal ulcers may be treated with over-the-counter drugs, whereas stomach ulcers may require prescription therapy. Your doctor must identify the type of ulcer you have before proposing a course of treatment.
  • The position of these two within the digestive system is the primary distinction between them. A duodenal ulcer affects the first portion of the small intestine or duodenum, whereas a gastric ulcer affects the lining of the stomach.
  • While gastric ulcers cause extreme agony, vomiting, and bleeding, duodenal ulcers just give a burning feeling that can be soothed by food or a cold beverage.


In younger and middle-aged adults, the formation of gastric ulcers—which are sometimes triggered by too much stomach acid—is more common. They may result in bleeding, nausea, and excruciating discomfort. Gastric ulcer sensation is frequently described as burning or biting. Usually, duodenal ulcers are painless. Chronic Helicobacter pylori infection, an overactive parietal cell, and non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen are frequently linked to gastric ulcers.

Low amounts of stomach acid, which can occur when using acid-blocking medicine, can cause duodenal ulcers. Chronic conditions including diabetes and Crohn's disease can also result in duodenal ulcers. If you experience persistent stomach pain, see your doctor right away so they can make a diagnosis and recommend treatment. If you periodically feel nauseous or sick to your stomach, it can be wise to temporarily cut back on your diet. Pay attention to your body's warning signs!



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"Difference Between Duodenal Ulcer and Gastric Ulcer." Diffzy.com, 2023. Mon. 20 Mar. 2023. <https://www.diffzy.com/article/difference-between-duodenal-ulcer-and-gastric-ulcer-807>.

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