Difference Between Advil and Motrin

Edited by Diffzy | Updated on: September 03, 2023


Difference Between Advil and Motrin

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For many years, over-the-counter medications have been highly well-liked. These medications can now be bought without a prescription from a doctor, thanks to legislative approval. Additionally, these medications belong to many classes that are designed to treat common illnesses and complaints. Since they are generally regarded as safe to use with little instruction and do not have extremely major side effects or difficulties when used, they do not require prescriptions. Like other medicines, they should never be taken regularly for an extended period. Antipyretics and anti-inflammatory pills, also referred to as NSAIDs (Non-steroidal Anti-inflammatory pills), are the most popular over-the-counter drugs. These medications are available over the counter because they are intended to treat pain and fever, which are the most frequent complaints among people. NSAIDs come in a wide range of varieties. While some of them have identical traits, others have different outcomes. Advil and Motrin may differ slightly from the rest of them.

Advil Vs. Motrin

Ibuprofen, a popular NSAID, is sold under the brand names Advil and Motrin, but there are major distinctions between the two in terms of how the body is treated. You must keep in mind, nevertheless, that the therapeutic effects and nature of these medications are relatively similar. The earliest of the two Ibuprofen brands to be created is thought to be Advil. As a result, it takes more time to have a therapeutic impact. There is no set time frame for a drug’s therapeutic effect because this depends on the individual using it. Advil has been reported to lower fever a little more quickly than Tylenol, even though they are both the same. However, further evidence is required to support this claim. The more recent brand of ibuprofen, Motrin, works similarly to Advil. Given that Motrin acts quicker, the only difference may be how long it takes to have a therapeutic impact.

Difference Between Advil and Motrin in Tabular Form

OwnerThe Advil brand is owned by Pfizer.The Motrin brand is owned by Johnson and Johnson.
Recent RecallsIn March 2012, Advil Liqui-Gels was recalled. (Affecting 650,000 bottles)Motrin Infant Drops- September 2013 recallMotrin Infants’ Drops- Recall in 2010.Due to quality issues in 2008-2009 and allegations of a cover-up, Motrin had a “phantom” recall.
DevelopmentAdvil was created first, takes longer to take effect, and lowers fever more quickly.Because it is more recent, Motrin has quicker therapeutic effects.
ExamplesIbuprofen with diphenhydramine, an antihistamine used in Motrin PM to promote sleep.Combining ibuprofen and the decongestant pseudoephedrine, Advil Cold & Sinus.

What is Advil?

Advil is an NSAID or nonsteroidal anti-inflammatory medicine. Ibuprofen works by lowering hormones that lead to pain and inflammation in the body. Advil is used to treat a variety of diseases, such as headaches, toothaches, backaches, arthritis, menstrual cramps, and minor injuries that are accompanied by pain or inflammation. Advil can be taken by both adults and kids who are at least two years old. Consult a doctor if the youngster is younger than 2 years old.


Never take more than the prescribed amount. An ibuprofen overdose can cause harm to your intestines or stomach. Use the least medication necessary to reduce your temperature, swelling, or discomfort.

Before Taking this Medicine

Advil can make you more likely to get a deadly heart attack or stroke, even if you don't have any risk factors for such events. Taking this medicine while having coronary artery bypass graft surgery (CABG) or right afterward is not recommended. Additionally, Advil might cause fatal stomach or intestinal bleeding. While taking this drug, these symptoms can appear quickly, especially in elderly people. If you've ever had a severe allergic response or an asthma attack after taking aspirin or another NSAID, you should steer clear of using Advil if you're sensitive to ibuprofen. Inquire with a doctor or chemist if it is okay for you to use this medication if you have ever had:

  • Diabetes, heart disease, high blood pressure, high cholesterol, or smoking.
  • A blood clot, stroke, or heart attack.
  • Stomach bleeding or ulcers.
  • Allergies
  • If aspirin is being taken to avoid a heart attack or stroke

Ibuprofen should not be taken while pregnant unless specifically advised to do so by a physician. NSAID use during the last 20 weeks of pregnancy may cause serious heart or kidney issues for the unborn child in addition to pregnancy complications. Without consulting a doctor, never give Advil to a child under the age of two.

How Should I Take Advil?

Follow the instructions on the bottle for Advil precisely, or use it as your doctor has advised. Use the lowest dose possible that will still cure your ailment. Your stomach or intestines can become damaged by an ibuprofen overdose. Ibuprofen's maximum recommended dose for adults is 3200 milligrams per day, divided into 4 maximum doses, or 800 milligrams per dose. The age and weight of a child influence how much ibuprofen to give them. Pay close attention to the dosage recommendations on the Junior Strength Advil label for your child's age and weight. If you have any questions, consult a physician or a chemist. Advil may be taken with food or milk to lessen an unpleasant stomach. The oral suspension should be shaken before each dose is taken. Use the accompanying dosage syringe or medication dose-measuring equipment.

Side Effects

Seek emergency medical attention if you experience symptoms of an Advil allergy, such as hives, breathing difficulties, swelling of the face or neck, or a severe skin response, such as fever, sore throat, burning eyes, skin pain, or a red or purple skin rash with blistering and peeling. Get quick medical help if you suffer a heart attack or stroke symptoms: Slurred speech, swelling legs, feeling out of breath, and abrupt numbness or paralysis on one side of the body are all signs of a heart attack.

If you have, Stop taking Advil and contact your physician right away.

  • Alterations to your vision
  • Breathlessness (even with light exertion)
  • Swell or rapidly gain weight
  • A skin rash, regardless of how minor
  • Gastrointestinal bleeding symptoms include bloody or tarry feces, bloody coughing, or vomit that resembles coffee grounds
  • Liver issues can cause jaundice (yellowing of the skin or eye), dark urine, upper stomach pain, itching, fatigue, flu-like symptoms, loss of appetite, and clay-colored feces.
  • Pale skin, feeling dizzy or out of breath, having problems focusing, and low red blood cells (anemia)
  • renal issues include infrequent or infrequent urine, painful or difficult urination, ankle or foot edema, and fatigue or shortness of breath.

Common Advil side effects may include:

  • Nausea, vomiting, gas
  • Bleeding
  • Dizziness, headache

What is Motrin?

Menstrual cramps, arthritis, headaches, tooth pain, muscle aches, and muscle spasms are just a few of the problems that can be treated with ibuprofen. It is also used to treat minor aches and pains that are caused by the common cold or flu, as well as to lower fever. Ibuprofen is an NSAID or nonsteroidal anti-inflammatory drug. Some naturally occurring inflammatory chemicals are stopped, which is how it works. Reduced temperature, pain, and edema are benefits of this influence. If you have a persistent condition like arthritis, talk to your doctor about using different medications or non-drug treatments to reduce your pain. Check out the Warning section, too. Read the ingredients label even if you have already used the product. There's a chance the manufacturer altered the ingredients.

How to Use Motrin Oral?

Before taking this medication, if you are using an over-the-counter product, read all the instructions on the product package. Before beginning to use ibuprofen and each time you obtain a refill, if your doctor has recommended it, read the Medication Guide your pharmacist provided. Ask your doctor or chemist any queries you may have.

A full glass of water (8 ounces/240 milliliters) should be consumed with this drug orally, often every 4-6 hours, unless your doctor instructs you differently. After taking this medication, do not lie down for at least 10 minutes. Take this drug with food, milk, or an antacid if you have stomach distress while taking it.

The dosage will depend on your health and how well you respond to treatment. To reduce the chance of stomach bleeding and other adverse effects, take this medication for the shortest time possible at the lowest effective dose. Never use this medication over what your doctor or the package label advises, either in terms of dosage or frequency. If your disease, such as arthritis, is ongoing, keep taking this medication as directed by your doctor. 

Their weight determines the dosage of ibuprofen for children. Consult the package recommendations for the recommended dosage based on your child’s weight. If you need assistance picking a non-prescription product or if you have any issues, speak with your chemist or doctor.

For some conditions (including arthritis), persistent usage of this drug may be necessary for up to two weeks before you start to feel its full effects. If you take this drug "as needed" (as opposed to on a regular schedule), keep in mind that painkillers work best when they are taken as soon as the first signs of pain arise. Waiting until the pain has worsened may prevent the medication from working as effectively. If your condition worsens or persists, or if you have any reason to believe you might be suffering from a serious medical condition, seek emergency medical assistance.

Side Effects

There can be headaches, nausea, vomiting, constipation, diarrhea, dizziness, tiredness, and stomach discomfort. If any of these adverse effects persist or worsen, let your doctor or chemist know as soon as you can. Remember that if your doctor has recommended this medication, it is because they believe you will benefit more than the risk of negative effects. Numerous users of this medication claim that there are no serious side effects. Taking this medication may cause your blood pressure to rise. Check your blood pressure often, and inform your doctor if the numbers are abnormal.

Very rarely will taking this drug result in a severe allergic response. However, you should immediately seek medical assistance if you have any severe adverse reaction symptoms, such as fever, swollen lymph nodes, rash, itching, or swelling (especially of the face, tongue, or neck), significant disorientation, or trouble breathing.


Before using ibuprofen, aspirin, or any other NSAID (such as naproxen or celecoxib), let your doctor or chemist know if you have any allergies. There is a chance that inactive substances in this product will cause allergic reactions or other problems. Speak to your chemist for additional information. This medicine may cause stomach bleeding. You may be more prone to develop gastrointestinal bleeding if you frequently smoke and drink alcohol while taking this medicine. Quit smoking and drink responsibly. Speak to your doctor or pharmacy for additional details. As a result of this treatment, you can become more sensitive to the sun. Limit your time in the sun. Don't use tanning beds or sunlamps.

The Main Difference Between Advil and Motrin in Points

  • Advil is the brand name owned by Pfizer. On the other hand, Motrin is the brand name owned by Johnsons and Johnsons.
  • Both brands are available in various forms and dosages (200 mg, 400mg, 800mg) but vary in dosage, form, and strength according to their chemical reactions.
  • The inactive ingredients of Advil and Motrin are different from each other. It depends on their compounds and manufacturing.
  • Advil was developed earlier than Motrin.
  • Advil takes a longer time to affect. On the other hand, Motrin has quicker therapeutic effects.


All three ibuprofen brand names- Motrin, Motrin IB, AND Advil. Are, thus, equally potent. As a result of the fact that they are on the same medication, taking Motrin, Motrin IB, and Advil at the same time increases the risk of experiencing side effects such as stomach ulcers and bleeding. Other NSAIDs like Aleve (naproxen) Motrin, and Advil shouldn’t be taken concurrently. Ibuprofen (Motrin, Motrin IB, Aleve) is less likely to hurt the heart if used in dosages lower than 1200 mg/day.


  • https://www.webmd.com/drugs/2/drug-4387-9368/motrin-oral/ibuprofen-oral/details
  • https://www.drugs.com/medical-answers/motrin-advil-difference-3122169/#:~:text=Official%20answer&text=There%20is%20no%20real%20difference,names%20for%20the%20drug%20ibuprofen.


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"Difference Between Advil and Motrin." Diffzy.com, 2024. Thu. 13 Jun. 2024. <https://www.diffzy.com/article/difference-between-advil-and-motrin>.

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