Difference Between Aleve and Ibuprofen

Edited by Diffzy | Updated on: April 30, 2023


Difference Between Aleve and Ibuprofen

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Both Aleve and Ibuprofen are under the category of over-the-counter (OTC) drugs that provide temporary pain relief for a variety of conditions, including back pain, fever, headache, inflammation, and several other moderate to severe pains. The duration of action is one of the key distinctions between Aleve and ibuprofen. Aleve is a long-acting medication intended to treat chronic illnesses, whilst Ibuprofen is short-acting and more suited for treating acute pain. Without consulting their doctors, millions of individuals use painkillers whenever they feel like it, which is harmful to their health. Ibuprofen and Aleve are two of the most popular painkillers, along with aspirin and others. Every time a person feels pain in their body, they take them. Different medications include various chemical ingredients that may be harmful to our bodies and our health.

Aleve vs. Ibuprofen

Because Aleve takes longer to take action, it is more likely than ibuprofen to result in gastrointestinal (GI) adverse effects. The best NSAID (nonsteroidal anti-inflammatory medicine) for children is ibuprofen. The main difference between ibuprofen and naproxen, the active component in Aleve, is that the latter is deemed to be safer for people with a history or risk of cardiovascular disease, whilst the former is not. Naproxen is the active ingredient in Aleve. The fact that naproxen lasts longer than ibuprofen is another distinction. Both kinds of non-steroidal anti-inflammatory medicines are available over-the-counter. Different medications have varying chemical components that have varying impacts on our bodies. Although these medications have various mechanisms of action, they all reduce bodily pain in the end.

Many people seem to disregard the adverse effects of medications as long as they relieve their discomfort. Aleve is dosed every 8 to 12 hours after the previous consumption since its half-life is longer than that of ibuprofen, which must be taken every 4 to 6 hours after the previous intake. Aleve is dosed every 8 to 12 hours after the previous consumption since its half-life is longer than that of ibuprofen, which must be taken every 4 to 6 hours after the previous intake. Since they are NSAIDs, using them often and in excess increases the risk of heart failure. They could also result in stomach issues.

Difference Between Aleve and Ibuprofen in Tabular Form

Parameters of Comparison Aleve Ibuprofen
Common Name Naproxen. The generic name for Advil and Motrin is Itself.
Forms available as oral capsules and tablets. present as a suspension, chewable pill, capsule, or solution.
Half-Life 18 Hours 4 Hours
Date of Approval 11th January of 1994 19th September of 1974
Manufactured By Bayer Produced Widely.

What is Aleve?

Naproxen is the active component of Aleve, a brand-name medication used for short-term pain treatment. The main component of over-the-counter pain relievers like Advil and Motrin is ibuprofen. The nonsteroidal anti-inflammatory medicine Aleve, also known by its generic name Naproxen, is used to treat a variety of pains, including headache, osteoarthritis, migraine, fever discomfort, and others. The pharmacological name for a different NSAID is ibuprofen; popular brand names for ibuprofen include Advil and Motrin. Aleve is the brand (trade) name for naproxen. Aleve is a brand name for the generic medication naproxen. Aleve is a brand name for the drug naproxen. Its physiological effects are comparable to those of ibuprofen. Since Aleve has grown to be such a household brand, hardly one asks for naproxen. Even some people have no idea what they are ingesting when they take Aleve. People carry it in their pockets so they may get it right away if they experience discomfort in a bodily area. It is an anti-inflammatory medication that provides rapid headache relief.

Women also use it to ease period cramps. Since Aleve is a brand name for the generic medicine naproxen, it is preferable to contrast the effects of the two drugs with ibuprofen. However, the brand name Aleve has grown to be so well-known that customers often ask for this sodium naproxen by that name. Similar to ibuprofen, Aleve is an anti-inflammatory medicine that reduces pain, primarily headache pain. Some women use it to treat menstruation cramps as well. Aleve reduces pain or inflammation over a longer length of time since it is long-acting but has a delayed onset. This medication's beginning dosage is 220 mg, however, if that amount is ineffective for you, you may take another 220 mg in two hours. To lessen the negative effects of naproxen, patients should take the 250mg, 275mg, 375mg, 500mg, and 550mg tablets and 125mg per 5ml oral solution precisely as directed. The main active component of Aleve is naproxen, which helps to lessen mild to severe bodily pain. This substance works by lowering the body's production of prostaglandins, which are in charge of regulating fevers, inflammation, and discomfort. Because Aleve prevents the production of certain enzymes that promote the synthesis of prostaglandins in the body, it effectively reduces pain. Knowing the strength and dosage of Aleve you need to take to get good pain relief is the first thing you should do. Second, eight ounces of water should be consumed immediately after taking this medication for efficient absorption and distribution. Aleve should also be taken with meals to prevent the development of an upset stomach after ingestion. It is advised to use this medication just as much as is required to ease any uncomfortable physical symptoms you may be experiencing. To prevent potential medication interactions and adverse effects, it is not advised to use Aleve in addition to other painkillers.

Given that it falls within the group of nonsteroidal anti-inflammatory medicines, it is strongly suggested that those with a history of peptic ulcers avoid using this medication. Due to the increased danger of stomach ulcers in such individuals, tight denial was necessary. In addition to this, Aleve is produced by a single producer and was given legal approval on January 11th, 1994. As its effects last longer, it is appropriate for treating the persistent condition of severe pains. Even if used for a short period, the medicine may lead to dependency and tolerance if not taken as directed by the doctor. Anyone who uses the substance regularly will go through withdrawal. Aleve's physical withdrawal effects might last up to 60 days or 48–72 hours. The amount and duration of Naprosyn consumption affect the withdrawal symptoms. A common pain reliever with a high yearly prescription rate is Naprosyn medicine. Although it is impossible to get a Naproxen high, this does not indicate that the drug cannot be abused. The medicine may be easily purchased from the drugstore. It is crucial to get medical care from rehab experts if one is struggling with drug misuse.

What is Ibuprofen?

Ibuprofen is maybe the most popular medication that individuals use without thinking twice to relieve pain. The same basic idea underlies all of the brand names, including Motrin, Advil, and many more. It functions similarly to aspirin in that it reduces prostaglandin synthesis. However, compared to taking aspirin, there is less esophageal and stomach lining discomfort. Ibuprofen is thus more effective in reducing pain, particularly in those who may have stomach ulcers or who have acid reflux syndrome. You don't need a doctor's prescription to use this drug. It is available as intravenous solution, oral suspension, oral (chewable) tablets, oral tablets, and oral capsules. Ibuprofen should not be used for an extended period as it may raise the risk of stomach-related adverse effects. Ibuprofen is undoubtedly one of the most often used medications that individuals take without thinking to treat pain. It is sold under several different brand names, including Motrin and Advil, but they all have the same impact, whether it is favourable or negative.

Similar to how aspirin works, it lowers prostaglandin synthesis. It works similarly to aspirin in this manner. Ibuprofen, as opposed to aspirin, reduces the thickness of the oesophagus and stomach lining. Ibuprofen is thus more effective than other painkillers in treating acid and ulcer pain. Ibuprofen is regarded as a short-acting NSAID because of how quickly it starts to work. It is the best NSAID for children since it works better for the treatment of acute pain. It is necessary to provide ibuprofen pills or capsules with every four to six hours. This medication aids in lowering and suppressing bodily aches and pains brought on by any number of conditions, including osteoarthritis, migraines, fever, and other inflammatory pains. In the year 1974, on September 19, it received legal approval. However, this medication just serves as a pain reliever rather than a treatment for arthritis. It will also be used by women to alleviate uncomfortable menstruation cycles. Fever relief is another purpose for ibuprofen. Ibuprofen is often used for pain treatment.

This may include discomfort brought on by pulling a muscle, tendonitis (tendon inflammation), or bursitis (expansion of a fluid-filled sac between a tendon and the skin or bones). Ibuprofen is also used to treat headaches, toothaches, knee, back, and foot pain as well as pain after surgery. Ibuprofen is sometimes used to treat arthritis-related symptoms such as pain, stiffness, and edoema. Your risk of a deadly heart attack or stroke may rise if you use ibuprofen. Below 100 mg/kg, toxic consequences are uncommon, but over 400 mg/kg, they may be severe or even fatal. 39 Large dosages, nevertheless, do not always mean that the clinical course will be fatal. Your stomach or intestines might get damaged by an ibuprofen overdose. Only take the tiniest dose of medicine required to reduce your discomfort, swelling, or temperature. Ibuprofen at low doses is just as effective for treating the conditions that are often treated with over-the-counter drugs such as aspirin and paracetamol. Due to its relatively broad range of indications, high level of tolerance, and safety, ibuprofen is appropriate for self-medication. The first member of the propionic acid derivative family to be made available as a superior Aspirin substitute was ibuprofen in 1969. Though less frequent than those from aspirin or indomethacin, nausea, vomiting, and gastric pain are still the most frequent adverse effects.

Difference Between Aleve and Ibuprofen In Points

  • While Ibuprofen itself is a generic term for Advil and Motrin, Naproxen is the name given to Aleve.
  • Aleve is only available in two forms, the oral capsule and the tablet, but Ibuprofen is available in a variety of forms, including a solution, capsule, suspension, and oral tablets that may be chewed as well as regular ones.
  • Any drug's half-life is the length of time it takes for its plasma concentration to drop to half of its starting value. Aleve has a half-life of up to 18 hours whereas Ibuprofen only has a half-life of up to 4 hours.
  • Ibuprofen and Aleve both received their first approvals on different dates: Ibuprofen on September 19, 1974, and Aleve on January 11, 1994.
  • In contrast to Ibuprofen, which is produced by several generic manufacturers, Aleve is made by a single company called Bayer.


Both medications function fairly similarly and aid in lessening or eliminating bodily aches and pains by blocking the release of prostaglandins, which are responsible for pain and inflammation. The two medications have different dosages. Ibuprofen is accessible without a prescription at dosages of 200 mg and 400 mg, but larger doses are only available with a doctor's prescription. Both NSAIDs, if routinely used at high dosages, increase the risk of heart failure. Both are capable of causing stomach issues. Aleve offers longer-lasting pain relief than ibuprofen in terms of its pain-relieving qualities. The primary distinction between ibuprofen and aleve is that the former is a brand name for naproxen, whilst the latter is the salt name. Both Advil and Aleve are NSAIDs that are efficient in treating pain and inflammation. Both medications can decrease core body temperature and lessen a fever.

As both medications target the COX enzymes, people shouldn't take Advil and Aleve at the same time. As a result, combining the two medications just raises the possibility of adverse effects without providing any additional benefits. NSAIDs should not be used by anybody who is pregnant or who has certain underlying medical disorders during the third trimester. Despite this, both drugs have comparable adverse effects and a warnings list. Despite this, both drugs have comparable adverse effects and a warnings list.



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"Difference Between Aleve and Ibuprofen." Diffzy.com, 2024. Mon. 10 Jun. 2024. <https://www.diffzy.com/article/difference-between-aleve-and-ibuprofen-864>.

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